The goal of this research was to judge the character and extent of reproducible and transparent research practices in neurology publications. The NLM catalog was used to establish MEDLINE-indexed neurology journals. A PubMed search of those journals was performed to retrieve publications over a 5-year interval from 2014 to 2018. A random pattern of publications was extracted. Two authors performed information extraction in a blinded, duplicate style utilizing a pilot-tested Google kind.
This kind prompted information extractors to find out whether or not publications offered entry to gadgets akin to research supplies, uncooked information, evaluation scripts, and protocols. In addition, we decided if the publication was included in a replication research or systematic evaluation, was preregistered, had a battle of curiosity declaration, specified funding sources, and was open entry.
Our search recognized 223,932 publications assembly the inclusion standards, from which 400 had been randomly sampled. Only 389 articles had been accessible, yielding 271 publications with empirical information for evaluation. Our outcomes point out that 9.4% offered entry to supplies, 9.2% offered entry to uncooked information, 0.7% offered entry to the evaluation scripts, 0.7% linked the protocol, and 3.7% had been preregistered. A 3rd of sampled publications lacked funding or battle of curiosity statements.
No publications from our pattern had been included in replication research, however a fifth had been cited in a scientific evaluation or meta-analysis.Currently, published neurology research doesn’t constantly present info wanted for reproducibility. The implications of poor research reporting can each have an effect on affected person care and enhance research waste. Collaborative intervention by authors, peer reviewers, journals, and funding sources is required to mitigate this drawback.
Unravelling Functional Neurology: an outline of all published paperwork by FR Carrick, together with a essential evaluation of research articles on its impact or profit.
Functional Neurology (FN), based by FR Carrick, is an method utilized by some chiropractors to deal with a mess of circumstances through the nervous system together with the mind.
However, it appears to lack simply obtainable scientific proof for its medical validity.1) To outline the matters of FR Carrick’s publications, 2) to outline the proportion of articles which can be research research, case research, abstracts and convention papers, 3) to outline what number of of those are medical research research that purported or appeared to cope with the impact or good thing about FN, 4) in these research, to determine whether or not the design and general research methodology had been appropriate for research into the impact or good thing about FN, and 5) to explain the proof obtainable in relation to the medical impact or good thing about FN, taking into consideration seven minimal methodological standards.
A literature search was executed on Pubmed from its inception until October 2018, supplemented by a search on Scopus and ResearchGate to search out all published paperwork by FR Carrick. We recognized their sorts and matters, retaining for a essential evaluation full textual content scientific articles showing to check impact/good thing about FN procedures, subjecting them to a fundamental high quality evaluation (scoring 0-7). Results from research of methodologically acceptable normal could be taken into consideration.We discovered 121 published texts, 39 of which had been full scientific research articles. Of these, 23 handled matters regarding FN. Fourteen articles reported on medical validity however solely seven included a management group. The methodological high quality of those seven articles was low, ranging between 1.5-Four out of seven. We due to this fact didn’t additional report the outcomes of those research.We discovered no acceptable proof in favour of impact/good thing about the FN method. We due to this fact don’t suggest its promotion as an evidence-based methodology. Further research on this matter needs to be performed in collaboration with unbiased scientific establishments utilizing generally accepted research strategies.PROSPERO This evaluation was registered in PROSPERO